The new BIOFLOAT™ cell culture surface for spheroid culture

In many areas of biomedical research, in vitro models are indispensable. The most conventional form is the two-dimensional cell culture. Discrepancies often occur when transferring the results to an entire organism. The aim of the three-dimensional cell culture is therefore to close this gap between the in vitro and in vivo situation.

Spheroid cultures offer a simple and cost-effective variant of the 3D cell culture. The cells form a three-dimensional cellular aggregate with pronounced cell-cell and cell-matrix contacts.

The new BIOFLOAT™ cell culture surface makes it possible for you to produce perfect spheroids quickly and reproducibly. 

The BIOFLOAT™ surface features a highly anti-adhesive property. This makes it possible for the cultivated adherent cells to form primarily cell-cell contacts without adhering to the surface of the vessel – it forms an anti-adhesive coating. 

Spheroids cultivated using the BIOFLOAT™ surface have a very even round shape. In addition, the formation of exactly one spheroid per well can be achieved. Both of these features lead to a high reproducibility of your results. This makes BIOFLOAT™ particularly suitable for high throughput analyses where it is especially important to examine exactly one symmetrical spheroid per well.

The robustness of the BIOFLOAT™ coating greatly facilitates daily work. Even multiple washing steps or mechanical action from a pipette tip do not impair the performance of the BIOFLOAT™ cell culture surface.

BIOFLOAT™ is used in a variety of fields such as cancer and stem cell research, in the preclinical phase of drug research and in toxicological studies. Spheroid cultures improve the efficiency and reliability of preclinical cell models in these applications.